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Other controlled research has been more mixed, with some trials finding little change in certain oxidative-stress markers [2]

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However, injections are typically used for whole-body peptide protocols, while GHK-Cu topicals provide targeted application for cosmetic enhancement

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10.1186/s12943-020-01258-7 Summary Keywords ulcerative colitis, GHK-Cu, SIRT1/STAT3 pathway, co-culture system, network pharmacology, molecular docking Citation Mao S, Huang J, Li J, Sun F, Zhang Q, Cheng Q, Zeng W, Lei D, Wang S and Yao J (2025) Exploring the beneficial effects of GHK-Cu on an experimental model of colitis and the underlying mechanisms