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Research from the STEP programme (semaglutide), SCALE studies (liraglutide), and SURMOUNT trials (tirzepatide) consistently demonstrates significant reductions in waist circumference, which correlates with abdominal fat loss
Sources: VA Research, "Diabetes drug from Gila monster venom" (2019)
The gut microbiota to the brain axis in the metabolic control
In the STEP 1 semaglutide trial (Wilding et al., NEJM , 2021) and the SURMOUNT-1 tirzepatide trial (Jastreboff et al., NEJM , 2022), nausea affected roughly 44% of semaglutide patients and about 24% of tirzepatide patients at the maximum dose
Our GLP-1 syringe complete guide covers needle selection in detail
Electrolyte balance becomes particularly important during GLP-1 therapy
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