Meals become functional rather than compulsive
Srenson's thinking was coloured by the fact that a previous drug, Redux, approved in 1996 by the FDA for weight loss and launched with great fanfare, had to be withdrawn a year later after it was found to cause major heart attacks and to be largely ineffective
The GI side effects and hormonal disruption from combining a dual and triple agonist would be significant and unpredictable
This mechanism is well documented in the prescribing information (Summary of Product Characteristics) for licensed GLP-1 receptor agonists such as semaglutide (Wegovy, Ozempic) and tirzepatide (Mounjaro), available via the electronic Medicines Compendium (eMC)
Personalized medical advice is key never adjust your dosage or stop medication without professional guidance
The only difference may be in the vial size or the specific concentration of the lyophilized powder, which affects how much water you add