semaglutide prediabetes progression to diabetes step trial Efficacy and safety of once-weekly 2·4 mg versus placebo in people with obesity and (STEP 10): a randomised, double-blind, placebo-controlled, multicentre phase 3 Delaying Type 1 Diabetes Progression

And I think whats so valuable about that is we dont generally think of weight and body composition as being related to exactly the function of the communication between the gut microbiome, the nervous system and the immune system, really, and metabolic system

This represents a massive increase in bioavailability, potentially elevating topical applications to levels approaching injectable delivery

These data come from Cosmos, a dataset created in collaboration with a community of Epic health systems representing more than 300 million patient records from 1,900 hospitals and more than 42,000 clinics from all 50 U.S

[DOI] [PMC free article] [PubMed] 105

doi: 10.1101/gad.1499107

They empower individuals to feel more comfortable in their own skin, which can have profound effects on confidence, social interactions, and overall happiness