Overview of the HGF/c-MET inhibitors currently used in melanoma treatment with references to the in vitro, in vivo and clinical studies is in Table 1
Leishear, K., Boudreau, R
Blockade of Met metabolism or loss of STAT3 significantly inhibits ILC2s function
J Neurochem 92(4):798806 Heppner KM, Kirigiti M, Secher A, Paulsen SJ, Buckingham R, Pyke C, Knudsen LB, Vrang N, Grove KL (2015) Expression and distribution of glucagon-like peptide-1 receptor mRNA, protein and binding in the male nonhuman primate (Macaca mulatta) brain
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While these studies are promising, more large-scale clinical trials are needed to assess the potential of increasing ergothioneine intake to improve cognitive health and address brain diseases