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Compared to NZW mice, the expression of the transferrin receptor 24p3R in the renal tubules of NZB/W mice was reduced, while transferrin expression and ferritin expression were increased, consistent with increased iron accumulation and compensatory downregulation of uptake pathways

In summary, oxidative stress drives the occurrence and progression of CVDs, and the GSH system is positively involved in antioxidant activity, which is beneficial to their treatment and prognosis

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Quercetin alleviates acute kidney injury by inhibiting ferroptosis

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