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While singly-housed animals may experience stress that impacts metabolism, body weight, and adiposity 65,66,67,68,69 , the singly-housed animals in this study were treated identically (to the best of the experimenters ability) to minimize and equalize stress across all animals and reduce confounding variables

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For cohort 1, the Ontario Drug Benefit (ODB) database was used to identify patients who were prescribed vitamin B12 injections

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An amount of 2.5 mg/mL Sh-Polypeptide 9 upregulated -catenin levels and downregulated IL-1 and caspase-3 levels in DPCs