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The Phase 2b MARIPOSA trial evaluated oral bedtime doses of AD109 in adults with mild to severe OSA and included patients with or without obesity and those with or without prior use of PAP therapy

[DOI] [PubMed] [Google Scholar] 59.de Wit H., Bodker B., Ambre J

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Ironically, those with diagnosed Type 2 diabetes appear to do worse

Stop smoking Smoking directly relaxes the lower esophageal sphincter, increases acid production, reduces saliva (which normally neutralizes esophageal acid), and damages the esophageal lining