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The GLP-1 hormone is rapidly inactivated by the enzyme DPP-4, with a half-life of only 12 min
Experimental models suggest that GLP-1 receptor activation may modulate the hypothalamicpituitarygonadal axis by influencing GnRH activity and gonadotropin release
If you experience any concerns, discontinue use and consult your healthcare provider for personalized guidance
Mol Metab 2014;3:507-17.ArticlePubMedPMC 23
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After being produced by enteroglucagon-producing L cells in the lower gut in response to food intake, incretins travel to various receptors including the pancreas and cause glucose-dependent insulin release causing lowering of elevated blood glucose [1]
