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Authors Note: The authors recognize the fast-evolving nature of GLP-1 research and trends and will endeavour to ensure the article remains current with emerging GLP-1 RA data.

[238] The 10 mg dose is particularly likely to cause significant drowsiness that may impair reaction time, concentration, and motor coordination

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What Is the SURMOUNT-5 Trial

Comparative realworld studies likewise suggested substantial bodyweight reduction with tirzepatide relative to other incretinbased therapies or matched controls [14, 15, 16]