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Frankly, there is a lot of misinformation on the internet about the MTHFR gene mutations, so I will explain the peer-reviewed research studies here

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17 Study participants received a standard oral (50 gram) sucrose load and randomized to placebo or escalating doses of D-allulose (2.5, 5.0, 7.5, 10.0 grams)

Hippocampal and hypothalamic sections from PTZ-treated animals were characterized by severe histopathological alterations and, intensely, increased the ezrin immunolabeled astrocytes

Furthermore, it resulted in tumours with reduced levels of cysteine-dependent metabolites (hypotaurine) and increased levels of ophthalmic acid, which is synthesized in the absence of cysteine 32,33 (Fig