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Severe deficiency can lead to a type of brain damage that presents as a soreness in the mouth, numbness or stiffness, shooting pains, strange hot and cold sensations and a needles-and-pins sensation
Post-translational modification status: neddylation of CUL5 serves as a critical activation switch (41, 42), and dysregulation of this process represents an upstream event determining its functional trajectory
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Injections are administered by a registered nurse or physician assistant
In a randomized controlled study, daily supplementation of vitamin B-12 and folic acid was found to increase cognitive function
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