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Fenfluramine, one of the earliest weight loss drugs, was found over time to be associated with valvular heart disease [48] and was withdrawn from the market by the FDA

Tumor markers like PSA, CA-125, or CEA may be worth checking in individuals with relevant risk factors, though their usefulness for screening in healthy individuals remains debated

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But as the pounds melt away, some people are noticing a loss of volume and a decrease in skin elasticity in the curvier parts of their bodies

"I think that there are a lot of people out there who have never tried these GLP-1 drugs and are maybe waiting for the pills to come out," said Dr