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The FLOW trial established kidney protection

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Treatment discontinuation due to side effects occurred in 4.3%, 7.1%, 6.2%, and 2.6% of participants in the 5, 10, 15 mg, and placebo groups, respectively [18]

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According to the Wegovy Summary of Product Characteristics (SmPC), treatment should be discontinued if a patient has not lost at least 5% of their initial body weight after 12 weeks on the maintenance dose (2.4 mg once weekly)