Journal of Antioxidant Research, 34(5), 1253-1265
This was first explored by Balthasar and colleagues, who in 2005 proved that specific inhibition of the IgG:FcRn interaction by use of a murine mAb (mouse IgG1, clone 4C9) with V regions specific for rat 2m generated by Bjorkman and colleagues could deplete endogenous IgG levels in rats [113, 114]
Proteomic identification and characterization of hepatic glyoxalase 1 dysregulation in non-alcoholic fatty liver disease
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Dos Santos, L
(26, 27) Poor detoxification: The liver is vital for protein synthesis, protein breakdown/utilization, and detoxification, as well as amino acid metabolism