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Eur J Clin Invest 54(12):e14292 Virani SS, Newby LK, Arnold SV, Bittner V, Brewer LC, Demeter SH et al (2023) 2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the management of patients with chronic coronary disease

Lake et al., 1984

In de eerste weken kun je tijdelijk last hebben van: Misselijkheid Buikklachten Verstopping of diarree Meestal wordt dit snel minder

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Initial dosing starts at 2.5 mg weekly to improve tolerability and is titrated every 4 weeks in 2.5 mg increments to a maximum of 15 mg, providing six dosing options: 2.5 mg 5 mg 7.5 mg 10 mg 12.5 mg 15 mg The initial low dose is not intended as the full therapeutic dose, but to reduce gastrointestinal side effects while patients adapt

Follow any site-rotation guidance provided by your trial team