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A direct comparison in mice demonstrated that sequential prime-boost vaccination with their three constructs (6 vaccinations in total) induced a stronger antibody response than simultaneous vaccination (prime and then boost with a mixture of all three, 2 vaccinations in total) [149]

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Abstract Alzheimers disease (AD) has become a major disease contributing to human death and is thought to be closely related to the aging process

(2014) characterized the role of senescent cells in tissue biology, demonstrating that senescent cell accumulation is associated with functional changes in aging tissues and providing the rationale for senolytic approaches [2]

We found that only the K39R mutation evident upregulated TFRC protein level (Fig

Therefore, CYS could be another limiting factor in the synthesis of glutathione, although supplementation with CYS must be carefully considered due to its possible toxicity (Reference Janky, Varga and Hermann78)