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Mild effects like warmth, metallic taste, or lightheadedness can occur

The Overall Hospital Quality Star Rating methodology would be unchanged through step eight with the exception of redesignating paragraph (d)(5) as (6), and paragraph (d)(6) as (5) (assignment of star ratings using K-means clustering as described previously in this section), with the cap being applied as a new step nine: Any hospital that is assigned 5 stars in step eight but has a lowest quartile Safety of Care score (based on at least three Safety of Care measures) would be reassigned to 4 stars

Some people view this as a barrier

However: No large, peer-reviewed human trials exist demonstrating proven benefit

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Similar findings for Cx43 at the cell membrane have also been reported 44