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Serious or theoretical risks: Pancreatitis signals have been observed in GLP-1 trials (rare)

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It has also been found that meningococcal IgA protease can translocate to the nucleus of the host cell because of the presence of a nuclear localization signal

Testing equipment cannot always detect this degradation through visual inspection, meaning a frozen dose may look acceptable but function poorly

10.1016/S1474-4422(17)30158-8 Lancet Neurol

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