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Others may maintain the weight loss they achieved while on the medication

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GIP-overexpressing mice demonstrate reduced diet-induced obesity and steatosis, and improved glucose homeostasis (PLoS ONE)

This interval allows: GI side effects (nausea, vomiting, diarrhea) from the current dose level to subside The body to adapt to the rate of gastric emptying at that dose Clinicians to assess tolerability before increasing further Time to reach maximum dose week 20 (after five four-week steps: 1mg, 2mg, 4mg, 8mg, 12mg)

This dual action is crucial to its success, allowing the medication to leverage the benefits of both hormones for improved outcomes