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The study was designed in two parts

Notably, the increase in BAT temperature and EE was totally suppressed by GCGR or GLP-1R antagonism, as well as by pharmacological ATGL inhibition or its deficiency in adipose tissue in parallel to a reduction in UCP1 levels

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Li X, Wang Y, Liu W, Mai K, Xu W, Zhang Y, Ai Q (2022) Dietary L-carnitine regulates liver lipid metabolism via simultaneously activating fatty acid oxidation and suppressing endoplasmic reticulum stress in large yellow croaker (Larimichthys crocea) fed with high-fat diets

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Platt OS, Brambilla DJ, Rosse WF, et al