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Disadvantages Slower onset: Peak blood levels take longer to achieve compared to IM injection

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A perfect concentration calculation means nothing if you denature the peptide during mixing

We simulated hyperhomocysteinemia artificially (that is, we treated it as a parameter in the simulations), increasing Hcy levels to around 400% of the physiological reference value

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It is known to activate telomerase, which helps maintain telomere length in cells