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Initial small trials from 2016 to 2017, including EXSCEL, FIGHT, and LIVE, were not supportive of the use of GLP-1RAs in HFrEF with negative outcomes related to cardiovascular events [53,54,55]

They slow gastric emptying and support healthy glucose regulation, triggering a hormone that keeps food in your stomach longer which may help decrease appetite and support the feeling of fullness

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Clinical trials show semaglutide achieves an average of 15% total body weight loss over 68 weeks

I weighed in at 156 pounds, and as of today, I am 132 pounds