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In addition, the results indicated essential roles of GPX in controlling ROS homeostasis by regulating intracellular H 2 O 2 levels, maintaining GSH/GSSG balance, and promoting antioxidant enzyme activity

The increased surface HLA-I expression on -cells may be a driver of T1D pathogenesis, as self-reactive CD8 + T cells must recognize peptide-HLA-I (pHLA-I) complexes on -cells to trigger lysis

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Sluming, V., Barrick, T., Howard, M., Cezayirli, E., Mayes, A., & Roberts, N