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However, many studies and meta-analyses suggested that individuals with NAFLD experienced significant risks for subclinical and clinical cardiovascular events, even after adjustment for atherosclerotic cardiovascular disease (ASCVD) risk factor covariates, establishing ASCVD together with extrahepatic malignancies (mostly gastrointestinal and thyroid) as the leading causes of morbidity and mortality in individuals with less advanced disease [1315]

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HPC = Hippocampus

Expanding the genetic code for site-specific lysine lactylation

The role of the SoxC family in neuronal development is not fully understood and it was suggested that SoxC proteins control the establishment of pan-neuronal gene expression (Bergsland et al., 2006) in contrast to proneural bHLH proteins that have been linked to the control of neuronal subtype identity (Berninger et al., 2007)