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Downregulation of SLC7A11 disrupts cysteine metabolism, leading to decreased intracellular cystine and GSH levels, impairing GPX4 activity and triggering lipid peroxide accumulation and ferroptosis (79,81,82)

The RDA for Vitamin B12 for adults is set to 2.4 mcg (2.6 mcg in pregnancy and 2.8 mcg while breastfeeding) and represents the amount needed to prevent a damaging Vitamin B12 deficiency

In conclusion, the combination of deep learning and radiomics in the field of OA holds great promise for improving diagnostic accuracy, treatment planning, and patient outcomes