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Also, BPC 157 counteraction includes damages induced by both cyclooxygenase (COX)-1 and COX-2 blockers [30] and markedly enhanced adaptive cytoprotection [63,64]

Animal studies spanning over 20 years show gastric ulcer healing, tendon repair, muscle regeneration, and neuroprotection with minimal toxicity, even at doses 10 to 100 times the therapeutic range (Sikiric et al., Curr Pharm Des 2018)

Notice something important about the higher doses

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Preclinical evidence from the Sikiric lab and collaborators describes protective effects against ethanol-induced gastric lesions, NSAID-induced enteropathy, and ileoileal anastomotic disruption in rat models, with the latter studied under the Pliva clinical-development code PL-14736 (Tkalcevi et al., 2007