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Moreover, IGF-1 knock-out mice exhibited significantly reduced expression of FSH receptors and consequently reduced aromatase expression and E2 secretion (68), indicating that IGF-signaling may regulate gonadotropin receptor expression

EBioMedicine 39:239254 Li J, Csibi A, Yang S et al (2015) Synthetic lethality of combined glutaminase and Hsp90 inhibition in mTORC1-driven tumor cells

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