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Randomised controlled trials involving GLP-1RA have not detected suicidality signals, but these studies were underpowered to detect rare events such as SIS, and they selectively exclude individuals with psychiatric comorbidity [23,24,25,26], which are prevalent in daily practice

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2023 CAB 006550, 10/23/25

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Results May Vary: Individual results vary based on age, baseline condition, starting weight, medication consistency, diet and exercise adherence, genetic factors, current medications, metabolic health, and other variables

& Zima, T