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Tirzepatide is a dual agonist and Semaglutide is a single agonist

The rationale is: First course: Addresses the existing senescent cell burden

Nonetheless, it is essential to recognize some distinctions between these two drugs

Ibuprofen can also impact kidney function and cardiovascular health, necessitating caution and medical supervision, especially in patients with preexisting conditions

Physical activity and exercise: Strategies to manage frailty

The guidance recognises that not all patients can immediately engage in structured exercise programmes due to mobility limitations, comorbidities, or other barriers, but encourages gradual increases in physical activity as weight loss progresses and functional capacity improves