Similarly, protein kinase C has been reported to activate the 2 1 mediated inside-out signaling pathway within a short amount of time 52
However, Eli Lilly rejected the accusation
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Proceedings of the National Academy of Sciences of the United States of America , 115(10), E2320E2328
These discoveries gain additional significance in light of recent evidence linking ferroptosis induction to enhanced immunotherapy efficacy, where GSH depletion-triggered ferroptosis can boost anti-tumor immunity through promoting the maturation of dendritic cells and the priming of CD8 + T cells [36]
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