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8177-0806), the Natural Science Foundation of Chongqing (cstc2021jcyj-msxmX0249), and Special Project for Enhancing Science and Technology Innovation Ability of Army Medical University (No

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The results showed that different linkers did not have a remarkable influence on the in vitro binding affinity of MDM2, while positively charged residues produced a significant enhancement in cell uptake and targeted capability in cellular reporter assay, indicating that positive charge is crucial for achieving cell viability using WT-p53 sequence-based stapled peptides

While NAC has antioxidant properties of its own, its biggest value comes from its ability to replenish glutathione levels

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