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Abstract Estrogen-related receptors (ERR//) are ligand-responsive nuclear receptors that coordinate oxidative metabolism, mitochondrial biogenesis, and substrate selection in energetically active tissues

doi: 10.1172/JCI57256 50 WiciskiMSochaMMalinowskiBWdkiewiczEWalczakMGrskiKet al

The tryptophan residue is at risk of oxidative degradation, forming impurities like kynurenine under photodegradation conditions

They're filled on separate production lines but use the same drug substance

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M., Rosenstock, J., Tran, M