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Instead of waiting for heart failure to occur, the threshold for pimobendan became left-side heart enlargement, an event which normally precedes CHF

A diagnosis of DKD should be made if repeat testing confirms an elevated albumin to creatinine ratio (greater than 2.5 mg/mmol in men or greater than 3.5 mg/mmol in women) or an eGFR less than 60 mL/min/1.73 m 2

doi: 10.1074/jbc.M708096200

The Institutional Review Board approved this study (UNM IRB#18-068) as described in the methods

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