[5] These are rat and cell-culture findings
Anti-aging, through resistance to and repair of ultraviolet (UV) and radiation damage to cells Glutathione detoxifies free radicals caused by UV and radiation, thus reducing damage and neutralizing reactivity, preventing further harm to cells
These effects are often mild to moderate and diminish over time with continued use
But only the R-isomer (R-ALA) is naturally produced in the body and actively participates in mitochondrial energy metabolism.12 Some studies suggest that R-ALA may be more bioavailable than standard racemic ALA though the clinical significance of this difference is still under investigation.17 In addition, anecdotal reports and small studies indicate that R-ALA may be easier on digestion, with fewer gastrointestinal side effects than standard racemic ALA, especially at higher doses.18 However, R-ALA is chemically unstable on its own
This reaction, known as mercapturic acid synthesis, increases the water solubility of the target compounds, facilitating their transport and excretion from the cell, a cornerstone of Phase II detoxification
But a persistent metallic taste in the mouth could indicate something more serious, for example, problems with liver or kidney function, an allergy to certain foods, or even anaphylaxis, a life-threatening allergic reaction
