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[DOI] [PubMed] [Google Scholar] 50.Borchert A., Kalms J., Roth S.R., Rademacher M., Schmidt A., Holzhutter H.-G., Kuhn H., Scheerer P

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Wegovy, as an injection, is FDA approved to: Reduce excess body weight and maintain long-term weight reduction in: Adults with obesity and adolescents ages 12 years and older with obesity Adults with overweight plus at least one weight-related medical condition, such as high blood pressure, type 2 diabetes, or high cholesterol Treat a serious type of fatty liver disease called noncirrhotic metabolic dysfunction-associated steatohepatitis (MASH) in adults with moderate to advanced liver scarring (stage F2 to F3 fibrosis) Lower the risk of major cardiovascular problems (such as heart attack, stroke, and heart-related death) in adults with established cardiovascular disease and obesity or overweight Contrave is FDA approved to: Reduce excess body weight and maintain long-term weight reduction in: Adults with obesity, defined as a body mass index (BMI) of 30 or higher Adults with a BMI of 27 or higher (overweight) plus at least one weight-related medical condition To recap, heres an at-a-glance comparison of FDA-approved uses for Wegovy vs