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According to KFF analysis of Centers for Medicare & Medicaid Services 2018-2022 Medicare Part D spending by drug increased from $57 Million to $5.7 Billion.[2] The June 13, 2024 article in Fierce Healthcare[3] on GLP-1 drugs noted that Blue Cross Blue Shield of Michigan will no longer cover these drugs starting in January 2025, and will be changing the prior authorization criteria starting in August 2024, for those members that are in large group fully insured commercial plans

METABOLIC RESEARCH RETATRUTIDE 20MG LYOPHILIZED Retatrutide is a triple receptor agonist (GLP-1, GIP, glucagon) investigated in laboratory metabolic-research settings

If your appetite is still suppressed, the medication is still working

6,24,25 Clinically, this manifests as depressed superior fat compartments with full inferior aspects encroaching on the inferior retaining ligament

Retatrutide targets three receptors GLP-1, GIP, and glucagon which is why clinics and influencers slapped the name GLP-3 on it

Semaglutide 2.4 mg (Wegovy) has received a NICE Technology Appraisal recommendation for use in adults with obesity under specific criteria (NICE TA875)