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The announcement that Novo was making more of its lower-dose starter product available as of this month came as the company reported its 2023 earnings, with sales up by 36% and operating profit up 44% at constant exchange rates, driven by enormous sales of Wegovy and Ozempic, the companys sister drug for diabetes

Important Safety Information for Wegovy (semaglutide) tablet Warning: Risk of Thyroid C-Cell Tumors In studies with mice and rats, semaglutide (the active ingredient in Wegovy, Ozempic, and Rybelsus) caused thyroid tumors, including thyroid cancer

This difference in molecular design likely contributes to the consistently superior outcomes seen with semaglutide across clinical trials, particularly for weight loss and HbA1c reduction

Ribeiro, R

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Blood 94:66a, 1999