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None of these ranges come from a published human clinical trial of IGF-1 LR3 they are extrapolated from preclinical work, the Increlex (mecasermin) clinical record, and decades of community reporting

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Methylation is necessary for many key biochemical reactions in the body, including: Detoxification (including estrogen and endocrine disruptor detoxification) Neurotransmitter production Genetic expression (more on this below) Amino acid (protein) metabolism Growth and development (including pregnancy) Producing phosphatidylcholine for cell membranes Producing creatine for muscle health and strength Producing glutathione for antioxidant protection The methylation process requires specific nutrients to produce methyl groups

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