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Since only partial information is available for each class, analyzing microarray experiments represents a valuable approach ahead of targeted expression studies

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Our results provide a possible mechanism in which upregulation of phosphorylated p53 and p16 maintain the cell cycle arrest of keloid fibroblasts, and FOXO4-DRI selectively induces apoptosis of keloid senescent fibroblasts by prompting p53-pS15 nuclear exclusion

The results of a preclinical study that examined the effect of SERT on body weight parameters in monkeys administered with SERT over an 18 mo period using a placebo-controlled, longitudinal, randomized study design showed that while the body weight and body fat composition of the placebo group increased, a decrease in body weight and fat composition was observed in the SERT treatment group[68]

Measurement response affects when effects become detectable