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If I understand rightly you haven't an absorption problem.So once on supplements or a richer B12 diet you can store and utilise b12 from your liver
External resources STEP 1 Trial: Once-Weekly Semaglutide in Adults with Overweight or Obesity (NEJM) STEP 5 Trial: Two-Year Effects of Semaglutide (Nature Medicine) Semaglutide Effects on Nutritional Metrics Including B12 (PMC) Semaglutide for Overweight and Obesity: A Comprehensive Review (PMC) For researchers serious about optimizing their semaglutide B12 protocol, SeekPeptides offers the most comprehensive resource available, with evidence-based guides, proven protocols, dosing calculators, and a community of thousands who have navigated these exact questions
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Bottom line: For the best results, take liposomal versions of both vitamin C and glutathione on an empty stomach in the morning to maximize cellular uptake
One area of interest that has emerged is the role of glutathione in combating COVID-19
