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Summary of the AOP Events: Molecular Initiating Events (MIE) Key Events (KE) Adverse Outcomes (AO) Relationships Between Two Key Events (Including MIEs and AOs) Network View Prototypical Stressors Life Stage Applicability Taxonomic Applicability Sex Applicability Overall Assessment of the AOP Biological plausibility, empirical support and quantitative understanding of the KERs and the evidence that uphold essentialities of KEs in this AOP were analyzed together for the overall assessment of an AOP

Klement, G

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However, data are limited to preclinical studies