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When this solution enters subcutaneous fat tissue (the layer beneath your skin), it can trigger mild inflammation and stimulate nerve receptors that signal a burning or stinging feeling

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One drawback to the GCSI is that is does not measure abdominal pain

Like all medications, Zepbound is associated with a range of side effects, most of which are gastrointestinal in nature

doi: 10.1186/s12933-018-0699-7 [DOI] [PMC free article] [PubMed] [Google Scholar] 12.Vaduganathan M, Fonarow GC, Greene SJ, et al

Involvement of insulin-like growth factor-I in the control of glucose homeostasis