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Both (4.5 mg/mouse per day twice daily) markedly reduced airway hyperreactivity, mucus production, neutrophilic inflammation, TNF-, IL-8, IL-17, eosinophilic inflammation, and Th2 responses in vivo [108]

The pseudo-natural product rhonin targets RHOGDI

Narveson JR, Haberl MD, Vannatta CN, Rhon DI

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First, scopolamine-induced cognitive impairment in young rats used in McCoy 2013 and Benoist 2014 as a pharmacological model of cholinergic disruption of spatial learning, with Morris water maze as the primary behavioral readout