doi: 10.1016/j.bbrc.2025.151529 16 BozkurtB.AhmadT.AlexanderK
Comparing Mounjaro to Other GLP-1 Treatments When comparing Mounjaro to established GLP-1 receptor agonists such as semaglutide (Ozempic, Wegovy) , dulaglutide (Trulicity) , and liraglutide (Victoza, Saxenda) , several key differences emerge
4.2 CXCL10 and the inhibitors Recent studies report a Th1/IFN- immune response in both human and a mouse model of vitiligo that involves elevated CXCL9, 10, and 11 productions, among which CXCL10 participated in the targeted migration of T cells (18), triggering an immune cell infiltration at the early stage (72), and involved in the downregulation of keratinocyte glycoprotein non-metastatic melanoma protein B (GPNMB) (75)
They may also increase the risk of adverse events or severe side effects due to improper dosing
After running through titles and abstracts and removing duplicates, 48 articles remained for full-text evaluation
When comparing metformin and semaglutide, the evidence points in a clear direction for most people who want meaningful weight loss