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In studies, L-theanine has shown a great safety profile, with animal studies employing doses that equate to around 50g/day in humans without any side effects.6 Another study, which combined L-theanine or placebo with the anti-anxiety medication fluoxetine, reported only mild drowsiness and occasional GI upset.7 Studies into Suntheanine bear similar results

Effects of folic acid and N-acetylcysteine on plasma homocysteine levels and endothelial function in patients with coronary artery disease

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Archives of General Psychiatry

The maximum plasma concentration of LC, LAC, and LPC occurred at 3.4, 2.4, and 3.8 hours after ingestion, respectively, and at quantities of 84.7, 12.9, and 5.1 mol/L, respectively