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While this is the case for most new medicines, its particularly important for those that work on several hormone pathways simultaneously

The net result of this triple activation is a broader and potentially more powerful metabolic response than earlier generation single or dual receptor agonists

Salazar J, Duran P, Garrido B, et al

Contact a clinician promptly rather than waiting these out

Pocai A, Carrington PE, Adams JR, Wright M, Eiermann G, Zhu L, Du X, Petrov A, Lassman ME, Jiang G, Liu F, Miller C, Tota LM, Zhou G, Zhang X, Sountis MM, Santoprete A, Capito E, Chicchi GG, Thornberry N, Bianchi E, Pessi A, Marsh DJ, Sinha RR

Common side effects were predominantly gastrointestinal, including nausea, diarrhea, constipation, and vomiting, primarily during dose escalation [45] [46]