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They found that upregulation of miR-181a-5p promoted M2 macrophage polarization, leading to a significant reduction in pancreatic damage and inflammation, thereby suggesting that M2 macrophages play a crucial protective role in resolving inflammation
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[16] Therefore, it is crucial to adhere to recommended dosages and to keep alpha-lipoic acid (especially the concentrated injection vials) out of reach of children
Methods: To determine the therapeutic potential of ATT-I, a murine model of colitis was established via dextran sulfate sodium (DSS) administration
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