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While using Vitamin C at night isn't harmful, it could potentially interact with other nighttime skincare products, such as retinol, and increase the risk of irritation

Quantitation of rate enhancements attained by the binding of cobalamin to methionine synthase

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Development 120 , 27492771 (1994)

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It works by influencing melanin synthesis and encouraging the production of lighter pigments instead of darker eumelanin