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Weight regain is common after discontinuation of GLP-1 drugs

Data extraction Data extraction was conducted independently by two reviewers using standardized forms, and any disagreements were resolved through discussion or, when necessary, consultation with a third reviewer

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The failure of broader or less specific agents, therefore, reinforces the central theme that therapeutic success in MIRI demands a highly targeted approach that addresses the specific downstream consequences of the initial oxidative insult

For example, M30 protected rat hepatocytes against ethanol-induced injury (Xiao et al., 2015)

GhrelinGLP-1 signaling improves glucose homeostasis in TMPRSS2 deficiency